Cardiotoxicity of anti-cancer drugs: cellular mechanisms and clinical implications
- Journal Title
- Frontiers in Cardiovascular Medicine
- Publication Type
- Review
- Abstract
- Cardio-oncology is an emerging field that seeks to enhance quality of life and longevity of cancer survivors. It is pertinent for clinicians to understand the cellular mechanisms of prescribed therapies, as this contributes to robust understanding of complex treatments and off-target effects, improved communication with patients, and guides long term care with the goal to minimise or prevent cardiovascular complications. Our aim is to review the cellular mechanisms of cardiotoxicity involved in commonly used anti-cancer treatments and identify gaps in literature and strategies to mitigate cardiotoxicity effects and guide future research endeavours.
- Publisher
- Frontiers
- Keywords
- anti-cancer (anticancer) medications; anti-neoplastic agent; cardio-oncology; cardiotoxicity; chemotherapy; pathophysiology
- Department(s)
- Medical Oncology
- PubMed ID
- 37745115
- Publisher's Version
- https://doi.org/10.3389/fcvm.2023.1150569
- Open Access at Publisher's Site
https://doi.org/10.3389/fcvm.2023.1150569- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2023-11-21 05:54:19
Last Modified: 2023-11-21 05:55:40