Development of an eHealth-enhanced model of care for the monitoring and management of immune-related adverse events in patients treated with immune checkpoint inhibitors
- Author(s)
- da Silva Lopes, AM; Colomer-Lahiguera, S; Darnac, C; Giacomini, S; Bugeia, S; Gutknecht, G; Spurrier-Bernard, G; Aedo-Lopez, V; Mederos, N; Latifyan, S; Addedo, A; Michielin, O; Eicher, M;
- Details
- Publication Year 2023-07-22,Volume 31,Issue #8,Page 484
- Journal Title
- Supportive Care in Cancer
- Publication Type
- Research article
- Abstract
- PURPOSE: The use of electronic patient-reported outcome (ePRO) data in routine care has been tied to direct patient benefits such as improved quality of care and symptom control and even overall survival. The modes of action behind such benefits are seldom described in detail. Here, we describe the development of a model of care leveraging ePRO data to monitor and manage symptoms of patients treated with immune checkpoint inhibitors. METHODS: Development was split into four stages: (1) identification of an underlying theoretical framework, (2) the selection of an ePRO measure (ePROM), (3) the adaptation of an electronic application to collect ePRO data, and (4) the description of an ePRO-oriented workflow. The model of care is currently evaluated in a bicentric longitudinal randomized controlled phase II trial, the IePRO study. RESULTS: The IePRO model of care is grounded in the eHealth Enhanced Chronic Care Model. Patients are prompted to report symptoms using an electronic mobile application. Triage nurses are alerted, review the reported symptoms, and contact patients in case of a new or worsening symptom. Nurses use the UKONS 24-hour telephone triage tool to issue patient management recommendations to the oncology team. Adapted care coordinating procedures facilitate team collaboration and provide patients with timely feedback. CONCLUSION: This report clarifies how components of care are created and modified to leverage ePRO to enhance care. The model describes a workflow that enables care teams to be proactive and provide patients with timely, multidisciplinary support to manage symptoms.
- Publisher
- Springer Nature
- Keywords
- Humans; Immune Checkpoint Inhibitors; Medical Oncology; *Mobile Applications; *Telemedicine/methods; Patient Reported Outcome Measures; Immune-related adverse events; Model of care; Patient-reported outcomes; Remote symptom management; Self-management support
- Department(s)
- Laboratory Research
- PubMed ID
- 37480546
- Publisher's Version
- https://doi.org/10.1007/s00520-023-07934-w
- Open Access at Publisher's Site
https://doi.org/10.1007/s00520-023-07934-w- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2023-10-19 04:37:30
Last Modified: 2023-10-19 04:37:56