Dietary patterns, malnutrition, muscle loss and sarcopenia in cancer survivors: findings from the UK Biobank
- Author(s)
- Curtis, AR; Livingstone, KM; Daly, RM; Brayner, B; Abbott, G; Kiss, N;
- Journal Title
- Journal of Cancer Survivorship : Research and Practice
- Publication Type
- Online publication before print
- Abstract
- PURPOSE: To identify dietary patterns derived from protein, polyunsaturated fatty acids (PUFA) and vitamin D and examine associations with malnutrition, low muscle mass and sarcopenia in cancer survivors. METHODS: This cross-sectional study included cancer survivors (n = 2415) from the UK Biobank (age [mean +/- SD] 59.7 +/- 7.1 years; 60.7% female). The Oxford WebQ 24-h dietary assessment estimated food and nutrient intakes. Reduced rank regression derived dietary patterns (response variables: protein [g/kg/day], PUFA [g/day] and vitamin D [mug/day]). Adjusted logistic regression analysis examined associations between dietary patterns and malnutrition, low muscle mass and sarcopenia. RESULTS: Three dietary patterns were identified: (i) 'high oily fish and nuts', characterised by higher oily fish and nuts and seeds intake; (ii) 'low oily fish', characterised by lower oily fish intake and higher potato intake; and (iii) 'meat and dairy', characterised by higher intake of meat, poultry and dairy. Eighteen percent of participants were malnourished, 5% had low muscle mass and 6.5% had sarcopenia. Odds of being malnourished were significantly lower with adherence to a 'high oily fish and nuts' pattern (OR: 0.57; 95% CI: 0.50, 0.65) and 'low oily fish' pattern (OR: 0.81; 95% CI: 0.73, 0.90). The 'meat and dairy' pattern was not associated with malnutrition. No dietary patterns were associated with low muscle mass or sarcopenia. CONCLUSIONS: Energy-rich dietary patterns were associated with lower odds of malnutrition in cancer survivors but did not influence muscle mass or sarcopenia risk. IMPLICATIONS FOR CANCER SURVIVORS: Better understanding of dietary patterns may improve cancer-related outcomes for cancer survivors.
- Keywords
- Cancer; Dietary patterns; Malnutrition; Muscle mass; Sarcopenia
- Department(s)
- Allied Health
- PubMed ID
- 37468793
- Publisher's Version
- https://doi.org/10.1007/s11764-023-01428-8
- Open Access at Publisher's Site
https://doi.org/10.1007/s11764-023-01428-8- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2023-10-17 06:55:51
Last Modified: 2023-10-17 06:58:32