Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors
Journal Title
Internal Medicine Journal
Publication Type
Online publication before print
Abstract
Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence-based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting. The primary aim of these consensus recommendations is to minimise the risk of vaccine-preventable infections and to outline alternative infection-prevention strategies where vaccination is problematic. We address disease-specific risks and propose timing considerations, including a pragmatic approach to clinical implementation.
Keywords
complement inhibitor; guidelines; immunisation; meningococcal; prophylactic antibiotics; vaccination
Department(s)
Infectious Diseases
Open Access at Publisher's Site
https://doi.org/10.1111/imj.70610
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2026-09-03 12:44:09
Last Modified: 2026-09-03 12:44:21
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