Time of infusion does not significantly impact outcomes following CAR T-cell therapy in large B-cell lymphoma
- Author(s)
- Dowling, MR; Scott, HW; Cliff, ERS; O'Leary, NL; Jeffrey, A; Dickinson, MJ; Cashion, C; Boyle, S; Li, J; Buss, T; MacDonald, R; Edelkina, A; Keir, MW; Belbachir, S; Westerman, DA; Tam, CS; Ho, PJ; Harrison, SJ; Barraclough, A; Inam, S; Blyth, E; Henden, AS; Vanguru, V;
- Details
- Publication Year 2026-05-07,Volume 147,Issue #19,Page 2272-2277
- Journal Title
- Blood
- Publication Type
- Research article
- Abstract
- In this retrospective analysis of 584 patients who received chimeric antigen receptor T-cell therapy for large B-cell lymphoma at 6 Australian centers, no association was found between time of infusion and outcome, accounting for confounders, suggesting minimal clinical impact of chronobiology in this setting.
- Publisher
- American Society of Hematology
- Keywords
- Humans; *Immunotherapy, Adoptive/methods; *Lymphoma, Large B-Cell, Diffuse/therapy/mortality; Retrospective Studies; Male; Female; Middle Aged; Aged; *Receptors, Chimeric Antigen; Adult; Treatment Outcome; Time Factors; Aged, 80 and over
- Department(s)
- Haematology
- Publisher's Version
- https://doi.org/10.1182/blood.2025032307
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2026-03-05 03:10:34
Last Modified: 2026-05-14 12:09:39