Establishing Linearity of the MOSkin Detector for Ultra-High Dose-per-Pulse, Very-High-Energy Electron Radiotherapy Using Dose-Rate-Corrected EBT-XD Film

Cayley, J; Engels, E; Charles, T; Bennetto, P; Cameron, M; Poder, J; Hausermann, D; Paino, J; Butler, D; Cutajar, D; Petasecca, M; Rosenfeld, A; Tan, YRE; Lerch, M

Author(s): Cayley, J; Engels, E; Charles, T; Bennetto, P; Cameron, M; Poder, J; Hausermann, D; Paino, J; Butler, D; Cutajar, D; Petasecca, M; Rosenfeld, A; Tan, YRE; Lerch, M;
Details: Publication Year 2025-07,Volume 15,Issue #14,Page 8101
Journal Title: Applied Sciences
Publication Type: Research article
Abstract: Very-high-energy electrons, coupled with ultra-high dose rates, are being explored for their potential use in radiotherapy to treat deep-seated tumours. The dose per pulse needed to achieve ultra-high dose rates far exceeds the limit of current medical linear accelerator capabilities. A high dose per pulse has been observed as the limiting factor for many existing dosimeters, resulting in saturation at doses far below what is required. The MOSkin, anexisting clinical quality assurance dosimeter, has previously been demonstrated as dose rate independent but has not been subjected to a high dose per pulse. Within this study, the MOSkins dose-per-pulse response was tested for linearity, with a dose per pulse as high as 23 Gy within 200 ns at the ANSTO Australian Synchrotron’s Pulsed Energetic Electrons for Research facility. While using EBT-XD film as a reference dosimeter, a dose rate dependence of the EBT-XD was discovered. Once confirmed and a correction factor established, EBT-XD was used as an independent reference measurement. This work presents confirmation of the MOSkin suitability for ultra-high dose-rate environments with an electron energy of 100 MeV, and a theoretical discussion of its dose-rate and dose-per-pulse independence; the MOSkin is the only detector suitable for both clinical quality assurance, and ultra-high dose-rate measurements in its standard, unmodified form.
Keywords: very-high-energy electron; VHEE; Geant4; ultra-high dose rate; UHDR; EBT-XD; FLASH; radiotherapy; MOSkin; MOSFET; dosimetry
Department(s): Physical Sciences
Publisher's Version: https://doi.org/10.3390/app15148101
Open Access at Publisher's Site: https://doi.org/10.3390/app15148101
Terms of Use/Rights Notice: Refer to copyright notice on published article.

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