Graft-Versus-Host Disease Mouse Models: A Clinical-Translational Perspective
- Author(s)
- Elliott, J; Koldej, R; Khot, A; Ritchie, D;
- Journal Title
- In: Sluyter, R. (ed) Graft-Versus-Host Disease: Methods and Protocols. Methods in Molecular Biology, vol 2907
- Publication Type
- Book section
- Abstract
- A variety of graft-versus-host disease (GVHD) models have been developed in mice for the purpose of allowing laboratory investigation of the pathobiology, prevention, and treatment of GVHD in humans. While such models are crucial in advancing our knowledge in this field, there are some key limitations that need to be considered when translating laboratory discoveries into the clinical context. This chapter will discuss current clinical practices in transplantation and GVHD and the relative strengths and weaknesses of mouse models that attempt to replicate these states.
- Publisher
- Springer US
- Department(s)
- Haematology
- Publisher's Version
- https://doi.org/10.1007/978-1-0716-4430-0_1
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2025-12-19 03:08:59
Last Modified: 2025-12-19 03:11:41