Factors associated with long-term functional and psychosocial outcomes in patients with non-Hodgkin lymphoma
- Author(s)
- Amatya, B; Dickinson, M; Khan, F;
- Journal Title
- Journal of Rehabilitation Medicine
- Publication Type
- Research article
- Abstract
- OBJECTIVE: To assess the long-term functional, psychosocial and participation outcomes in an Australian cohort of non-Hodgkin lymphoma (NHL) survivors. METHODS: A cross-sectional sample of adult NHL survivors at the Peter MacCallum Cancer Centre (between 2015 and 2020), participated by completing validated questionnaires. A series of analyses described their current level of function, psychosocial well-being, and participation. RESULTS: Of 129 participants (mean (M) +/- standard deviation (SD) age: 62.5 +/- 8.8 years), the majority (58%) had aggressive NHL and grade III-IV (72%), with time since diagnosis of 4.6 +/- 1.2 years. Participants reported ongoing issues after completion of treatment: fatigue (63%), bladder dysfunction (61%), cognitive impairment (53%), and NHL-related pain (46%). Most made good functional recovery (M +/- SD) (Functional Independent Measure-Motor: 79.5 +/- 8.2), reported minimal change in their negative emotional states, and NHL-specific quality of life (QoL) (Functional Assessment of Cancer Therapy-Lymphoma: 133.5 +/- 22.1). Participants were "well" adjusted to community living (Community Integration Measure: 42.2 +/- 7.4) and satisfied with their current life (Satisfaction with Life Scale: 26.3 +/- 6.0). Factors significantly associated with the poorer current level of function were: age at diagnosis < 60 years, time since NHL diagnosis > 4.5 years, and aggressive NHL type. CONCLUSION: Despite good functional recovery and adjustment in the community, NHL survivors report the presence of ongoing residual impairments and cognitive issues, which requires long-term rehabilitation-inclusive management.
- Publisher
- Medical Journals Sweden
- Keywords
- Adult; Humans; Middle Aged; Aged; *Quality of Life; Cross-Sectional Studies; Australia; *Lymphoma, Non-Hodgkin; Patients
- Department(s)
- Clinical Haematology
- PubMed ID
- 36852625
- Publisher's Version
- https://doi.org/10.2340/jrm.v55.4816
- Open Access at Publisher's Site
https://doi.org/10.2340/jrm.v55.4816- Terms of Use/Rights Notice
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Creation Date: 2023-09-12 07:43:53
Last Modified: 2023-09-12 07:44:44