Roles and responsibilities of registered nurses in the early recognition and management of sepsis in acute hospital settings: a scoping review

Lemoh, AY; Rashidzada, Z; Krishnasamy, M; Wilkinson, A; Blackwood, R; Rivalland, A; Ierano, C; Thursky, KA; Guccione, L

Author(s): Lemoh, AY; Rashidzada, Z; Krishnasamy, M; Wilkinson, A; Blackwood, R; Rivalland, A; Ierano, C; Thursky, KA; Guccione, L;
Details: Publication Year 2025-10-23,Volume 14,Issue #4,Page e003485
Journal Title: BMJ Open Quality
Publication Type: Review
Abstract: INTRODUCTION: Sepsis causes over 20% of deaths annually, with early recognition and management being key strategies to preventing patient deterioration. Despite being the largest group of hospital-based clinicians, the role of registered nurses (RNs) in sepsis remains poorly defined. OBJECTIVE: To describe the roles and responsibilities of RNs in early recognition and management of sepsis in acute hospital settings, applying the Action, Actor, Context, Target and Time (AACTT) Implementation Science Framework to specify nursing behaviours across domains, and identify evidence gaps to inform future research and practice. METHODS: The review was conducted using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. We searched Medline, EMBASE, CINAHL and PubMed for studies discussing the contribution of RNs in acute hospital-based sepsis care. Data were extracted and mapped to the AACTT framework domains. RESULTS: 27 (90%) of 30 included studies described RNs as the actor responsible for the action of sepsis screening. 26 studies (87%) described RN actions relating to timely care escalation and sepsis management. A broader range of actions was identified in resource-restricted contexts, with three (10%) studies reporting RN-initiated blood tests, chest X-rays, intravenous fluids and antimicrobials.Across 16 studies (53%), eight roles with dedicated focus on sepsis identification and management were identified; only one study outlined formal training requirements. Nurse practitioners were excluded here given their credentialed role and scope. CONCLUSION: Nurses perform essential actions in early sepsis recognition and management, with several RN roles focused on sepsis care identified. A broader scope of nurse-initiated actions was identified in resource-restricted contexts to meet clinical demand. There is potential for a greater scope of nursing actions in sepsis care for the benefit of patients and health services, but to achieve this, standardised training requirements need to be developed, and scope of practice defined.
Publisher: BMJ
Keywords: Humans; *Sepsis/diagnosis/nursing/therapy; *Nurse's Role; *Nurses/standards/statistics & numerical data/psychology; Hospitals/statistics & numerical data; *Early Diagnosis; Critical care; Implementation science; Nurses; Professional Role; Sepsis
Department(s): Infectious Diseases; Academic Nursing; Haematology; Health Services Research
Publisher's Version: https://doi.org/10.1136/bmjoq-2025-003485
Open Access at Publisher's Site: https://doi.org/10.1136/bmjoq-2025-003485
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2025-11-13 02:47:32

Last Modified: 2025-11-13 02:49:45