'Finding Comfort in Discomfort': A Qualitative Study of Cancer Clinicians and Researchers' Experiences of Conducting a Cancer Rapid Autopsy Program
Details
Publication Year 2025-05,Volume 34,Issue #5,Page e70175
Journal Title
Psycho-Oncology
Publication Type
Research article
Abstract
BACKGROUND: Rapid autopsy offers a tantalising opportunity to better characterise metastatic disease and determine how malignancies evade treatment. The CASCADE (CAncer tiSsue Collection After DEath) rapid autopsy program at the Peter MacCallum Cancer Centre, established in 2012, has conducted more than 100 autopsies. The experiences of clinicians and researchers who conduct this program can offer insight into how a unique program can be conducted sensitively and how their involvement impacts them personally and professionally. PURPOSE: To explore experiences of the clinicians and researchers involved in the CASCADE cancer rapid autopsy program. MATERIALS AND METHODS: A qualitative approach employing semi-structured interviews was used to collect data from clinicians and researchers working at the Peter MacCallum Cancer Centre. Inductive thematic analysis with team-based codebook development was used to generate findings. RESULTS: Participants (N = 20) described the benefits and burdens of involvement in a cancer rapid autopsy program, including strategies used to 'find comfort in discomfort'. Offering participation in CASCADE enhanced patient-clinician rapport. The goals of the CASCADE program helped participants overcome confronting experiences in the autopsy room and use of autopsy-derived tissue in the laboratory. Peer-support is essential to avoid burnout. CONCLUSION: The benefits outweighed the burdens of delivering a cancer rapid autopsy program, however, it is important that staff are well supported in their roles.
Publisher
Wiley
Keywords
Humans; Qualitative Research; Autopsy/methods; Female; *Neoplasms/pathology/psychology; Male; *Research Personnel/psychology; Middle Aged; *Attitude of Health Personnel; Interviews as Topic; Adult; cancer; metastasis; oncology; precision oncology; professional issues; qualitative; rapid autopsy
Department(s)
Familial Cancer Centre
Open Access at Publisher's Site
https://doi.org/10.1002/pon.70175
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2025-07-17 04:27:28
Last Modified: 2025-07-17 04:28:05
An error has occurred. This application may no longer respond until reloaded. Reload 🗙