AMPK CA(R)Sts a new light on amino acid sensing
- Author(s)
- Brown, KK;
- Details
- Publication Year 2021-11,Volume 40,Issue #21,Page e109575
- Journal Title
- EMBO Journal
- Publication Type
- Commentary
- Abstract
- AMP-activated protein kinase (AMPK) is recognized as a critical regulator of cellular energy metabolism impacted by AMP/ATP and ADP/ATP ratios, or glucose- and fatty acid-derived metabolites. However, its ability to sense alterations in amino acid levels is poorly understood. Recent work by Yuan et al (2021) identifies a novel mechanism of AMPK regulation responsive to changes in availability of the sulfur-containing amino acid cysteine.
- Keywords
- *AMP-Activated Protein Kinases/genetics/metabolism; *Amino Acids; Energy Metabolism; Fatty Acids; Glucose
- Department(s)
- Laboratory Research
- PubMed ID
- 34582060
- Publisher's Version
- https://doi.org/10.15252/embj.2021109575
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2025-06-19 06:51:03
Last Modified: 2025-06-19 06:51:41