"Do-not-resuscitate (DNR)" status determines mortality in patients with COVID-19
- Author(s)
- Alhatem, A; Spruijt, O; Heller, DS; Chokshi, RJ; Schwartz, RA; Lambert, WC;
- Details
- Publication Year 2021-05,Volume 39,Issue #3,Page 510-516
- Journal Title
- Clinics in Dermatology
- Publication Type
- Research article
- Abstract
- We investigatd the influence of do-not-resuscitate (DNR) status on mortality of hospital inpatients who died of COVID-19. This is a retrospective, observational cohort study of all patients admitted to two New Jersey hospitals between March 15 and May 15, 2020, who had, or developed, COVID-19 (1270 patients). Of these, 640 patients died (570 [89.1%] with and 70 [10.9%] without a DNR order at the time of admission) and 630 survived (180 [28.6%] with and 450 [71.4%] without a DNR order when admitted). Among the 120 patients without COVID-19 who died during this interval, 110 (91.7%) had a DNR order when admitted. Deceased positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients were significantly more likely to have a DNR order on admission compared with recovered positive SARS-CoV-2 patients (P < 0.05), similar to those who tested negative for SARS-CoV-2. COVID-19 DNR patients had a higher mortality compared with COVID-19 non-DNR patients (log rank P < 0.001). DNR patients had a significantly increased hazard ratio of dying (HR 2.2 [1.5-3.2], P < 0.001) compared with non-DNR patients, a finding that remained significant in the multivariate model. The risk of death from COVID-19 was significantly influenced by the patients' DNR status.
- Keywords
- *covid-19; Cohort Studies; Humans; *Resuscitation Orders; Retrospective Studies; SARS-CoV-2
- Department(s)
- Palliative Care
- PubMed ID
- 34518012
- Publisher's Version
- https://doi.org/10.1016/j.clindermatol.2020.11.013
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2025-05-23 04:02:50
Last Modified: 2025-05-23 04:04:10