Infliximab for Paradoxical Reactions in Pediatric Central Nervous System Tuberculosis
Details
Publication Year 2021-10,Volume 10,Issue #12,Page 1087-1091
Journal Title
Journal of the Pediatric Infectious Diseases Society
Publication Type
Case report
Abstract
Paradoxical reactions in central nervous system tuberculosis (CNS-TB) are associated with significant morbidity and mortality. We describe 4 HIV-uninfected children treated for CNS-TB with severe paradoxical reactions unresponsive to corticosteroids. All made recovery after treatment with infliximab, highlighting the safety and effectiveness of infliximab for this complication, and need for prospective trials.
Keywords
Adrenal Cortex Hormones; *Antitubercular Agents/adverse effects; Child; Humans; Infliximab/adverse effects; Prospective Studies; *Tuberculosis, Central Nervous System/drug therapy
Department(s)
Infectious Diseases
PubMed ID
34608937
Terms of Use/Rights Notice
Refer to copyright notice on published article.


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