Preventive medication deprescribing in advanced cancer patients approaching end of life

Author(s): McKenzie, J; Dunn, C; Gard, G; Le, B; Gibbs, P;
Details: Publication Year 2025-04,Volume 55,Issue #4,Page 673-676
Journal Title: Internal Medicine Journal
Publication Type: Research article
Abstract: Previous reports indicated many patients with advanced cancer and limited life expectancy have ongoing preventive medication prescription (PMP) of uncertain benefit and increased risk. Our review of palliative care oncology admissions found high rates of PMP (69%) at time of first palliative care admission, despite high rates of inpatient deprescription (88%) and death at a median of 16 days (interquartile range 10-45) following admission. Rates of PMPs did not vary by time from last systemic treatment (P = 0.29) or by prior palliative care involvement (P = 0.82). Physicians and the wider multidisciplinary care team may be missing deprescription opportunities for terminally ill patients.
Publisher: Wiley
Keywords: Humans; *Neoplasms/drug therapy; *Deprescriptions; *Palliative Care/methods; *Terminal Care/methods; Aged; Male; Female; Middle Aged; Aged, 80 and over; deprescribing; end‐of‐life care; oncology; palliative care
Department(s): Medical Oncology; Palliative Care
Publisher's Version: https://doi.org/10.1111/imj.70013
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2025-04-08 06:06:20

Last Modified: 2025-05-15 04:17:34