Strategies for the Management of Solitary Pulmonary Nodules: A Survey of Patient Preferences

Smith, Z; Barnett, SA; Gorelik, A; Pascoe, DM; Manser, RL

Author(s): Smith, Z; Barnett, SA; Gorelik, A; Pascoe, DM; Manser, RL;
Details: Publication Year 2022-05,Volume 113,Issue #5,Page 1670-1675
Journal Title: Annals of Thoracic Surgery
Publication Type: Research article
Abstract: BACKGROUND: Guideline-based strategies for evaluation of solitary pulmonary nodules are tailored to the likelihood of malignancy. Surveillance, biopsy, and resection are all reasonable approaches in fit individuals when the likelihood of malignancy is intermediate. Given the paucity of data demonstrating superior outcomes and important trade-offs among strategies, guidelines emphasize the importance of eliciting patient preferences and engaging in shared decision making; however, there is little literature on what patient preferences actually are. METHODS: This study conducted a cross-sectional, interview-administered questionnaire survey in 100 adults recruited from a metropolitan teaching hospital (The Royal Melbourne Hospital, Parkville, Victoria, Australia). The questionnaire used a hypothetical scenario designed to elicit patient preferences for different management strategies of solitary pulmonary nodules with a probability of malignancy between 10% and 70%. RESULTS: The mean age of participants was 62 years (range, 45 to 80 years), 56% were male, and 94% were current smokers or ex-smokers. Ninety-four percent completed all questions. At 10% probability of malignancy, 36.3% preferred surveillance, 42.4% preferred needle biopsy, and 21.2% preferred surgical resection. Preference for surgical resection increased to 53.5% and 86.2% when the probability of malignancy was 30% and 70%, respectively. Changes in the diagnostic yield of computed tomography biopsy significantly altered preferences when the probability of malignancy was 10% or 30%. CONCLUSIONS: The majority of participants surveyed expressed a preference for some type of biopsy over observation at all levels of solitary pulmonary nodule probability of malignancy evaluated. In an era of increasing solitary pulmonary nodule detection and patient-centered care, if confirmed in broader studies, these findings have considerable implications for processes of care and resource allocation.
Keywords: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Humans; *Lung Neoplasms/diagnosis/surgery; Male; Middle Aged; Patient Preference; *Solitary Pulmonary Nodule/diagnosis/pathology/surgery; Surveys and Questionnaires; Victoria/epidemiology
Department(s): Surgical Oncology; Internal Medicine
PubMed ID: 34033743
Publisher's Version: https://doi.org/10.1016/j.athoracsur.2021.04.094
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2025-04-04 06:56:54

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