Lacrimal gland pleomorphic adenoma with extensive necrosis
- Author(s)
- O'Rourke, MA; McKelvie, PA; Angel, CM; McNab, AA;
- Details
- Publication Year 2022-06,Volume 41,Issue #3,Page 378-381
- Journal Title
- Orbit
- Publication Type
- Case report
- Abstract
- Lacrimal gland pleomorphic adenomas (LGPA) are benign mixed tumors. Diagnosis is based on clinical and radiological findings which usually prompts complete excision of the lesion to minimise recurrence and a cumulative risk of malignant transformation. Necrosis in pleomorphic adenoma has been rarely reported in salivary gland PA, either spontaneously or due to iatrogenic interventions. Necrosis is suggestive of a malignant process and makes interpretation of histology specimens difficult. A 23 year old woman, while awaiting biopsy for a mass in the left lacrimal gland, which had been symptomatic for only several months, presented with acute pain and swelling of the left lateral lid. An incisional biopsy showed an inflamed lacrimal gland with focal necrosis and atypia of adjacent cytology and gland architecture. Subsequent excisional biopsy confirmed an LGPA with some inflammation but no necrosis. Necrosis may occur as an atypical presentation in LGPA.
- Keywords
- *Adenoma, Pleomorphic/diagnostic imaging/surgery; Adult; *Eye Neoplasms/diagnostic imaging/surgery; Female; Humans; *Lacrimal Apparatus/diagnostic imaging/pathology/surgery; *Lacrimal Apparatus Diseases/diagnostic imaging/surgery; Necrosis/pathology; Young Adult; Lacrimal gland; necrosis; pleomorphic adenoma
- Department(s)
- Pathology
- PubMed ID
- 33402001
- Publisher's Version
- https://doi.org/10.1080/01676830.2020.1867194
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2025-02-14 04:06:04
Last Modified: 2025-02-14 04:08:15