American Society of Transplantation and Cellular Therapy Series: #8-Management and Prevention of Non-Aspergillus Molds in Hematopoietic Cell Transplantation Recipients
Details
Publication Year 2025-04,Volume 31,Issue #4,Page 194-223
Journal Title
Transplantation and Cellular Therapy
Publication Type
Guideline
Abstract
The Practice Guidelines Committee of the American Society of Transplantation and Cellular Therapy partnered with its Transplant Infectious Disease Special Interest Group to create a guideline focusing on non-Aspergillus invasive molds, which are uncommon yet lethal invasive fungal diseases in the peri-hematopoietic cell transplant (HCT) period. We used a compendium-style approach by dissecting this broad, heterogeneous, and highly complex topic into a series of standalone frequently asked questions (FAQs) and tables. Adult and pediatric infectious diseases and HCT content experts developed, then answered FAQs, and finalized topics with harmonized recommendations. All the evidence for non-Aspergillus invasive mold infection is non-RCT and mostly level III, therefore there are no recommendation grades, and instead key references are provided. Through this format, this "8th" topic in the series focuses on the relevant risk factors, diagnostic considerations, prophylaxis, and treatment approaches relevant to rare mold infections in the pre- and post-transplant periods.
Publisher
Elsevier
Keywords
*Hematopoietic Stem Cell Transplantation/adverse effects; Humans; Mycoses/prevention & control; Invasive Fungal Infections/prevention & control/etiology; Societies, Medical; Risk Factors; Antifungal Agents/therapeutic use; Guideline; Hematopoietic cell transplant; Invasive fungal infection; Mold
Department(s)
Infectious Diseases
Open Access at Publisher's Site
https://doi.org/10.1016/j.jtct.2025.01.892
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2025-02-11 06:48:51
Last Modified: 2025-05-08 07:28:35

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