Lateral temporal bone resections for peri-auricular cutaneous squamous cell carcinoma: prognostic indicators and radiological predictive values

Kwok, MMK; Choong, KWK; Virk, J; Kleid, S; Magarey, MJR

Author(s): Kwok, MMK; Choong, KWK; Virk, J; Kleid, S; Magarey, MJR;
Details: Publication Year 2022-04,Volume 136,Issue #4,Page 297-303
Journal Title: Journal of Laryngology & Otology
Publication Type: Research article
Abstract: BACKGROUND: Lateral temporal bone resections are used in the management of locally advanced peri-auricular cutaneous squamous cell carcinomas, but there is still conflicting evidence regarding the staging, surgical and adjuvant treatment decisions. METHODS: A retrospective analysis was performed on all patients who underwent lateral temporal bone resection for cutaneous squamous cell carcinoma between January 2015 and December 2019 at a dedicated tertiary oncology referral centre. RESULTS: Twenty-nine patients were included, with a median age of 77 years. Computed tomography, magnetic resonance imaging and positron emission tomography showed good diagnostic accuracy in identifying disease in the parotid gland, external auditory canal and mastoid bone, but had poor sensitivity in identifying cervical nodal metastasis. Six patients had recurrence at a median of 4.8 months post-operatively. Tumour differentiation (p = 0.0040) and post-operative radiotherapy (p = 0.0199) were associated with significantly better recurrence-free survival. CONCLUSION: Lateral temporal bone resection for peri-auricular cutaneous squamous cell carcinoma requires careful surgical planning using clinico-radiological correlation, particularly in patients with poorly differentiated tumours.
Keywords: Aged; *Carcinoma, Squamous Cell/diagnostic imaging/pathology/surgery; *Head and Neck Neoplasms/pathology; Humans; Neoplasm Recurrence, Local/diagnostic imaging/pathology/surgery; Neoplasm Staging; Prognosis; Retrospective Studies; *Skin Neoplasms/diagnostic imaging/pathology/surgery; Temporal Bone/diagnostic imaging/pathology/surgery; Ear; Head; Head And Neck Cancer; Head And Neck Squamous Cell Carcinomas; Neck; Skin; Skull Base
Department(s): Surgical Oncology
PubMed ID: 34819182
Publisher's Version: https://doi.org/10.1017/S0022215121003704
Terms of Use/Rights Notice: Refer to copyright notice on published article.

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