Massive hypertriglyceridemia associated with paclitaxel; a case report
- Author(s)
- Koneshamoorthy, A; Hulse, D; Chong, CY; Krishnamurthy, B; Ananda, S; Hamblin, PS;
- Journal Title
- Gynecologic Oncology Reports
- Publication Type
- Case report
- Abstract
- This report describes a patient who developed massive hypertriglyceridemia (12,488 mg/dL or 141 mmol/L) during paclitaxel and carboplatin adjuvant chemotherapy for high grade serous fallopian tube carcinoma. Paclitaxel was thought to be the causative agent and she had normal triglyceride levels following a change to carboplatin and gemcitabine. To our knowledge, this is the highest reported triglyceride level associated with paclitaxel. Measurement of serum lipids should be considered in individuals receiving taxane chemotherapy, especially in those with type 2 diabetes mellitus or a history of dyslipidemia.
- Keywords
- Fallopian tube carcinoma; Hypertriglyceridemia; Paclitaxel
- Department(s)
- Medical Oncology
- PubMed ID
- 35782104
- Publisher's Version
- https://doi.org/10.1016/j.gore.2022.101030
- Open Access at Publisher's Site
https://doi.org/10.1016/j.gore.2022.101030- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-12-20 05:36:42
Last Modified: 2024-12-20 05:37:53