Theory Designed Strategies to Support Implementation of Genomics in Nephrology

Kansal, A; Quinlan, C; Stark, Z; Kerr, PG; Mallett, AJ; Lakshmanan, C; Best, S; Jayasinghe, K

Author(s): Kansal, A; Quinlan, C; Stark, Z; Kerr, PG; Mallett, AJ; Lakshmanan, C; Best, S; Jayasinghe, K;
Details: Publication Year 2022-10-21,Volume 13,Issue #10,Page 1919
Journal Title: Genes
Publication Type: Research article
Abstract: (1) Background: Genomic testing is increasingly utilized as a clinical tool; however, its integration into nephrology remains limited. The purpose of this study was to identify barriers and prioritize interventions for the widespread implementation of genomics in nephrology. (2) Methods: Qualitative, semi-structured interviews were conducted with 25 Australian adult nephrologists to determine their perspectives on interventions and models of care to support implementation of genomics in nephrology. Interviews were guided by a validated theoretical framework for the implementation of genomic medicine-the Consolidated Framework of Implementation Research (CFIR). (3) Results: Nephrologists were from 18 hospitals, with 7 having a dedicated multidisciplinary kidney genetics service. Most practiced in the public healthcare system (n = 24), a large number were early-career (n = 13), and few had genomics experience (n = 4). The top three preferred interventions were increased funding, access to genomics champions, and education and training. Where interventions to barriers were not reported, we used the CFIR/Expert Recommendations for Implementing Change matching tool to generate theory-informed approaches. The preferred model of service delivery was a multidisciplinary kidney genetics clinic. (4) Conclusions: This study identified surmountable barriers and practical interventions for the implementation of genomics in nephrology, with multidisciplinary kidney genetics clinics identified as the preferred model of care. The integration of genomics education into nephrology training, secure funding for testing, and counselling along with the identification of genomics champions should be pursued by health services more broadly.
Keywords: *Nephrology; Australia; Genomics; nephrology; theory designed strategies
Department(s): Health Services Research
PubMed ID: 36292804
Publisher's Version: https://doi.org/10.3390/genes13101919
Open Access at Publisher's Site: https://doi.org/10.3390/genes13101919
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2024-12-19 03:18:26

Last Modified: 2024-12-19 03:23:08