Assessment of response to PRRT including anatomical and molecular imaging as well as novel biomarkers

Author(s): Kong, G; Noe, G; Chiang, C; Herrmann, K; Hope, TA; Michael, M;
Details: Publication Year 2025-03,Volume 37,Issue #3,Page e13461
Journal Title: Journal of Neuroendocrinology
Publication Type: Review
Abstract: Peptide receptor radionuclide therapy (PRRT) is an effective treatment for both oncological and hormone control and is a widely accepted standard of care treatment for patients with neuroendocrine neoplasms (NEN). Its use is anticipated to increase significantly, and this demands accurate tools and paradigms to assess treatment response post PRRT. This article outlines the current role and future developments of anatomical, molecular imaging and biomarkers for response assessment to PRRT, highlighting the challenges and provides perspectives for the need to focus on a multimodality, multidisciplinary and individualised approach for patients with this complex heterogeneous disease.
Publisher: Wiley
Keywords: Humans; *Neuroendocrine Tumors/diagnostic imaging; *Molecular Imaging/methods; Receptors, Peptide/metabolism; Biomarkers, Tumor; Biomarkers; Radiopharmaceuticals; Prrt; molecular imaging; radiology; response
Department(s): Cancer Imaging; Internal Medicine; Medical Oncology
Publisher's Version: https://doi.org/10.1111/jne.13461
Open Access at Publisher's Site: https://doi.org/10.1111/jne.13461
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2024-12-17 03:06:43

Last Modified: 2025-04-08 06:06:10