Precision medicine for prostate cancer: An international perspective
- Author(s)
- Hamid, AA; Sweeney, CJ; Hovens, C; Corcoran, N; Azad, AA;
- Details
- Publication Year 2024-12,Volume 42,Issue #12,Page 392-401
- Journal Title
- Urologic Oncology
- Publication Type
- Review
- Abstract
- Greater personalization of cancer medicine continues to shape therapy development and patient selection accordingly. The treatment of prostate cancer has evolved considerably since the discovery of androgen deprivation therapy. The comprehensive profiling of the prostate cancer genome has mapped the targetable molecular landscape of the disease and identified opportunities for the implementation of novel and combination therapies. In this review, we provide an overview of the molecular biology of prostate cancer and tools developed to aid prognostication and prediction of therapy benefit. Modern treatment of advanced prostate cancer is reviewed as a paradigm of increasing precision-informed approach to patient care, and must be considered on a global scale with respect to the state of science and care delivery.
- Publisher
- Elsevier
- Keywords
- Humans; Male; *Precision Medicine/methods; *Prostatic Neoplasms/genetics/therapy/drug therapy; Prognosis; Biomarkers; Personalized therapy; Precision medicine; Prostate cancer
- Department(s)
- Medical Oncology
- Publisher's Version
- https://doi.org/10.1016/j.urolonc.2024.02.004
- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-12-12 03:29:02
Last Modified: 2024-12-12 03:29:12