A comparison of in-house and shared RapidPlan models for prostate radiation therapy planning

Claridge Mackonis, E; Sykes, J; Hardcastle, N; Espinoza, A; Brown, A; Perez, G; Evans, B; Sheehan, H; Haworth, A

Author(s): Claridge Mackonis, E; Sykes, J; Hardcastle, N; Espinoza, A; Brown, A; Perez, G; Evans, B; Sheehan, H; Haworth, A;
Details: Publication Year 2022-12,Volume 45,Issue #4,Page 1029-1041
Journal Title: Physical and Engineering Sciences in Medicine
Publication Type: Research article
Abstract: Knowledge-based planning (KBP) can increase plan quality, consistency and efficiency. In this study, we assess the success of a using a publicly available KBP model compared with developing an in-house model for prostate cancer radiotherapy using a single, commercially available treatment planning system based on the ability of the model to achieve the centre's planning goals. Two radiation oncology centres each created a prostate cancer KBP model using the Eclipse RapidPlan software. These two models and a third publicly-available, shared model were tested at three centres in a retrospective planning study. The publicly-available model achieved lower rectum doses than the other two models. However, the planning-target-volume (PTV) doses did not meet the local planning goals and the model could not be adjusted to correct this. As a result, the plans most likely to satisfy local planning goals and requirements were created using an in-house model. For centres without an existing in-house model, a model created by another centre with similar planning goals was found to be preferred. Variations in local planning practices including contouring, treatment technique and planning goals can influence the relative performance of KBP. The value of publicly available KBP models could be enhanced through standardisation of planning goals and contouring guidelines, providing information related to the planning goals used to create the model and increased flexibility to allow local adaptation of the KBP model.
Keywords: Male; Humans; Radiotherapy Planning, Computer-Assisted/methods; *Radiotherapy, Intensity-Modulated/methods; Radiotherapy Dosage; Retrospective Studies; Prostate; *Prostatic Neoplasms/diagnostic imaging/radiotherapy; Knowledge-based planning (KBP); Radiation oncology; RapidPlan; Shared models
Department(s): Physical Sciences
PubMed ID: 36063348
Publisher's Version: https://doi.org/10.1007/s13246-022-01151-1
Open Access at Publisher's Site: https://doi.org/10.1007/s13246-022-01151-1
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2024-10-16 06:19:40

Last Modified: 2024-10-16 06:21:19