Pretransplant MRD detection of fusion transcripts is strongly prognostic in KMT2A-rearranged acute myeloid leukemia
- Author(s)
- Loo, S; Potter, N; Ivey, A; O'Nions, JDr; Moon, R; Jovanovic, J; Fong, CY; Anstee, NS; Tiong, IS; Othman, J; Chua, CC; Renshaw, H; Baker, R; Fleming, S; Russell, NH; Ritchie, D; Bajel, A; Hou, HA; Dillon, RJ; Wei, AH;
- Journal Title
- Blood
- Publication Type
- Online publication before print
- Abstract
- Pre-transplant detection of KMT2Ar MRD ≥0.001% by quantitative PCR was associated with significantly inferior post-transplant survival (2-year RFS 17% vs 59%; p=0.001) and increased cumulative incidence of relapse (2-year CIR 75% vs 25%, p=0.0004).
- Department(s)
- Clinical Haematology; Pathology
- Publisher's Version
- https://doi.org/10.1182/blood.2024026605
- Open Access at Publisher's Site
https://doi.org/10.1182/blood.2024026605- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-10-03 03:25:54
Last Modified: 2024-10-03 03:37:44