Radiation-induced angiosarcoma-An unusual cause of recurrent pleural effusion

Author(s): Yun, JSW; McCracken, J; Wadhwa, V;
Details: Publication Year 2024-09,Volume 12,Issue #9,Page e70013
Journal Title: Respirology Case Reports
Publication Type: Case report
Abstract: Although rare, radiotherapy can induce secondary malignancies, such as radiation-induced angiosarcoma (RIAS), which is associated with a poor prognosis. Early detection is crucial for improving outcomes. The modified Cahan criteria are instrumental in diagnosing RIAS, which is ultimately confirmed through histological examination. We present a case of a middle-aged woman who developed RIAS after undergoing radiotherapy post-surgery and adjuvant chemotherapy for right-sided breast cancer. The patient presented with a rapidly reaccumulating right-sided pleural effusion, and RIAS was confirmed through pleural biopsy and aspirate. This case report highlights the pathway for establishing a diagnosis of RIAS and the need for early detection through clinical examination and surveillance imaging for patients following radiotherapy.
Publisher: Wiley
Keywords: angiosarcoma; breast cancer; pleural effusion; radiation therapy
Department(s): Medical Oncology; Ambulatory Services
Publisher's Version: https://doi.org/10.1002/rcr2.70013
Open Access at Publisher's Site: https://doi.org/10.1002/rcr2.70013
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2024-10-01 07:31:05

Last Modified: 2024-10-01 07:37:32