Living with low muscle mass and its impact throughout curative treatment for lung cancer: A qualitative study

Kiss, N; Ugalde, A; Prado, CM; Denehy, L; Daly, RM; Siva, S; Ball, D; Fraser, SF; Edbrooke, L

Author(s): Kiss, N; Ugalde, A; Prado, CM; Denehy, L; Daly, RM; Siva, S; Ball, D; Fraser, SF; Edbrooke, L;
Details: Publication Year 2024,Volume 19,Issue #7,Page e0304003
Journal Title: PLOS One
Publication Type: Research article
Abstract: OBJECTIVES: To 1) explore the experience of patients with lung cancer with low muscle mass or muscle loss during treatment and the ability to cope with treatment, complete self-care, and 2) their receptiveness and preferences for nutrition and exercise interventions to halt or treat low muscle mass/muscle loss. METHODS: This was a qualitative study using individual semi-structured interviews conducted using purposive sampling in adults with a diagnosis of non-small cell lung cancer (NSCLC) or small-cell lung cancer (SCLC), treated with curative intent chemo-radiotherapy or radiotherapy. Patients who presented with computed tomography-assessed low muscle mass at treatment commencement or experienced loss of muscle mass throughout treatment were included. Data were analysed using thematic analysis. RESULTS: Eighteen adults (mean age 73 ± SD years, 61% male) with NSCLC (76%) treated with chemo-radiotherapy (76%) were included. Three themes were identified: 1) the effect of cancer and its treatment; 2) engaging in self-management; and 3) impact and influence of extrinsic factors. Although experiences varied, substantial impact on day-to-day functioning, eating, and ability to be physically active was reported. Patients were aware of the overall importance of nutrition and exercise and engaged in self-initiated or health professional supported self-management strategies. Early provision of nutrition and exercise advice, guidance from health professionals, and support from family and friends were valued, albeit with a need for consideration of individual circumstances. CONCLUSION: Adults with NSCLC with or experiencing muscle loss described a diverse range of experiences regarding treatment. The types of support required were highly individual, highlighting the crucial role of personalised assessment of needs and subsequent intervention.
Publisher: PLOS
Keywords: Humans; Male; Female; Aged; *Lung Neoplasms/therapy/pathology; *Qualitative Research; *Carcinoma, Non-Small-Cell Lung/therapy/pathology; Middle Aged; Aged, 80 and over; Exercise; Small Cell Lung Carcinoma/therapy/pathology; Self Care
Department(s): Health Services Research; Radiation Oncology
Publisher's Version: https://doi.org/10.1371/journal.pone.0304003
Open Access at Publisher's Site: https://doi.org/10.1371/journal.pone.0304003
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2024-08-29 04:13:47

Last Modified: 2024-08-29 04:22:13