Quantitating and Characterizing the Effects of Epigenetic Targeted Drugs
- Journal Title
- In: O'Connor, O.A., Ansell, S.M., Seymour, J.F. (eds) Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice
- Publication Type
- Book section
- Abstract
- The epigenome plays a critical role in the biology of cancer and drugs that target various epigenetic regulators are increasingly entering clinical use. The past decade has witnessed an unprecedented expansion in our capacity to analyze epigenetic changes during cancer progression and in response to therapy. In this chapter, we review key technologies that can be applied to profile various aspects of chromatin biology and discuss concepts and considerations for data interpretation.
- Department(s)
- Laboratory Research
- Publisher's Version
- https://doi.org/10.1002/9781119819950.ch15
- Open Access at Publisher's Site
https://doi.org/10.1002/9781119819950.ch15- Terms of Use/Rights Notice
- Refer to copyright notice on published article.
Creation Date: 2024-08-20 06:08:17
Last Modified: 2024-08-20 06:56:56