Primary thoracic aorta angiosarcoma presenting with thromboembolism and progressive claudication despite anticoagulation
Details
Publication Year 2024-06,Volume 68,Issue #4,Page 421-423
Journal Title
Journal of Medical Imaging and Radiation Oncology
Publication Type
Case report
Abstract
Primary aortic angiosarcomas (PAA) are rare angiosarcomas, frequently diagnosed in advanced stages due to initial misdiagnosis. This case describes a 66-year-old woman, initially presenting with a distal thoracic aorta thrombus and symptomatic bilateral popliteal emboli. Despite initial management and therapeutic anticoagulation, she experienced progressive lower limb claudication and 12 months following initial presentation she re-presented with an obstructing distal thoracic aorta mass and metastatic disease. Histopathology confirmed metastatic epithelioid angiosarcoma. Despite urgent palliative radiotherapy, she died 6 weeks after diagnosis from complications of tumour thromboembolism. Suspicion for PAA should be raised in the case of thrombus in atypical segments (e.g. thoracic aorta) or progressive course despite anticoagulation. Multimodal imaging including MRI and FDG-PET is useful to distinguish from benign aetiologies.
Publisher
Wiley
Keywords
Humans; Female; *Hemangiosarcoma/diagnostic imaging/complications; Aged; *Aorta, Thoracic/diagnostic imaging; *Intermittent Claudication/etiology/diagnostic imaging; Fatal Outcome; *Anticoagulants/therapeutic use; *Vascular Neoplasms/diagnostic imaging/complications; Thromboembolism/diagnostic imaging; Diagnosis, Differential; Magnetic Resonance Imaging/methods; oncologic imaging; radiation oncology; vascular imaging
Department(s)
AYA Cancer Service; Radiation Oncology; Medical Oncology; Pathology
Terms of Use/Rights Notice
Refer to copyright notice on published article.


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Last Modified: 2024-08-06 08:24:44

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