Standardised definitions and diagnostic criteria for extranodal extension detected on histopathological examination in head and neck cancer: Head and Neck Cancer International Group consensus recommendations
Details
Publication Year 2024-07,Volume 25,Issue #7,Page e286-e296
Journal Title
Lancet Oncology
Publication Type
Review
Abstract
Detection of extranodal extension on histopathology in surgically treated head and neck squamous cell carcinoma indicates poor prognosis. However, there is no consensus on the diagnostic criteria, interpretation, and reporting of histology detected extranodal extension, which has contributed to conflicting evidence in the literature, and likely clinical inconsistency. The Head and Neck Cancer International Group conducted a three-round modified Delphi process with a group of 19 international pathology experts representing 15 national clinical research groups to generate consensus recommendations for histology detected extranodal extension diagnostic criteria. The expert panel strongly agreed on terminology and diagnostic features for histology detected extranodal extension and soft tissue metastasis. Moreover, the panel reached consensus on reporting of histology detected extranodal extension and on nodal sampling. These consensus recommendations, endorsed by 19 organisations representing 34 countries, are a crucial development towards standardised diagnosis and reporting of histology detected extranodal extension, and more accurate data collection and analysis.
Publisher
Elsevier
Keywords
Humans; *Head and Neck Neoplasms/pathology; *Consensus; *Delphi Technique; *Extranodal Extension/pathology; Squamous Cell Carcinoma of Head and Neck/pathology; Terminology as Topic
Department(s)
Radiation Oncology
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Refer to copyright notice on published article.


Creation Date: 2024-07-30 06:26:10
Last Modified: 2024-07-30 06:34:07

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