Precision medicine for prostate cancer: An international perspective
Journal Title
Urologic Oncology
Publication Type
Online publication before print
Abstract
Greater personalization of cancer medicine continues to shape therapy development and patient selection accordingly. The treatment of prostate cancer has evolved considerably since the discovery of androgen deprivation therapy. The comprehensive profiling of the prostate cancer genome has mapped the targetable molecular landscape of the disease and identified opportunities for the implementation of novel and combination therapies. In this review, we provide an overview of the molecular biology of prostate cancer and tools developed to aid prognostication and prediction of therapy benefit. Modern treatment of advanced prostate cancer is reviewed as a paradigm of increasing precision-informed approach to patient care, and must be considered on a global scale with respect to the state of science and care delivery.
Keywords
Biomarkers; Personalized therapy; Precision medicine; Prostate cancer
Department(s)
Medical Oncology
Terms of Use/Rights Notice
Refer to copyright notice on published article.


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