Guidelines of guidelines: focal therapy for prostate cancer, is it time for consensus?
Details
Publication Year 2023-01,Volume 131,Issue #1,Page 20-31
Journal Title
BJU International
Publication Type
Review
Abstract
OBJECTIVE: To provide a summary and discussion of international guidelines, position statements and consensus statements in relation to focal therapy (FT) for prostate cancer (PCa). METHODS: The European Association of Urology-European Association of Nuclear Medicine-European Society for Radiotherapy and Oncology-European Society of Urogential Radiology-International Society of Urological Pathology-International Society of Geriatric Oncology and American Urological Association-American Society for Radiation Oncology-Society of Urologic Oncology guidelines were interrogated for recommendations for FT. PubMed and Ovid Medline were searched for consensus statements. Only studies in English since 2015 were included. Reference lists of the included articles were also interrogated and a manual search for studies was also performed. RESULTS: Our results showed a lack of long-term randomised data for FT. International Urological guidelines emphasised the need for more high-quality clinical trials with robust oncological and toxicity outcomes. Consensus and positions statements were heterogenous. CONCLUSION: A globally accepted guideline for FT planning, technique and follow-up are still yet to be determined. Well-designed studies with long-term follow-up and robust clinical and toxicity endpoints are needed to improve our understanding of FT and create uniform guidelines to streamline management and follow-up.
Publisher
Wiley
Keywords
Male; Humans; United States; Aged; *Prostatic Neoplasms/therapy; *Urology; consensus; focal therapy; guidelines; prostate cancer; prostate carcinoma
Department(s)
Surgical Oncology
PubMed ID
36083229
Open Access at Publisher's Site
https://doi.org/10.1111/bju.15883
Terms of Use/Rights Notice
Refer to copyright notice on published article.


Creation Date: 2023-06-13 07:55:09
Last Modified: 2023-06-13 07:56:08

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