Subjective cognitive changes following premenopausal risk-reducing bilateral salpingo-oophorectomy
Details
Publication Year 2023-12,Volume 26,Issue #6,Page 625-631
Journal Title
Climacteric
Publication Type
Research article
Abstract
OBJECTIVE: Women at high risk of ovarian cancer are commonly advised to undergo risk-reducing bilateral salpingo-oophorectomy (BSO) prior to natural menopause. Cognitive symptoms during natural menopause transition are frequently reported; however, very few studies have examined cognitive changes following surgical menopause. To address this gap, we explored the cognitive experiences of women within 24 months post BSO. METHODS: This observational cross-sectional sub-study is part of a larger project, the Early Menopause and Cognition Study (EM-COG). We investigated perceived cognitive experiences in Australian women (n = 16) who underwent risk-reducing BSO using qualitative interviews. Thematic analysis was undertaken to identify key themes. RESULTS: Fifteen out of 16 participants (93.75%) reported changes to cognition within 24 months post BSO. The key cognitive symptoms reported were brain fog, memory and retrieval difficulties, slower processing speed as well as attention difficulties. Five participants (31.3%) experienced negative mood symptoms post BSO. CONCLUSION: Findings from this study suggest that women experience subjective cognitive changes within 24 months post BSO. This period could be a vulnerable time for women's cognitive health. While these findings need to be confirmed by a large prospective study, our research indicates that psychoeducation and awareness will be helpful in managing cognitive symptoms after surgical menopause.
Keywords
Female; Humans; Salpingo-oophorectomy; Prospective Studies; Cross-Sectional Studies; Australia; Menopause/psychology; *Ovarian Neoplasms/surgery; *Genital Diseases, Female; Ovariectomy; Surgical menopause; bilateral salpingo-oophorectomy; brain fog; memory; subjective cognitive experiences
Department(s)
Familial Cancer Centre
Open Access at Publisher's Site
https://doi.org/10.1080/13697137.2023.2256659
Terms of Use/Rights Notice
Refer to copyright notice on published article.


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